Lubilax 24mcg Capsule

✔️ Uses of Lubilax 24mcg Capsule

• Constipation
• Irritable Bowel Syndrome

✔️ How Lubilax 24mcg Capsule works?

Lubilax 24mcg Capsule contains ‘Lubiprostone’ that works by retaining the water inside the intestines, which causes the intestine's easy movement. It also acts by drawing water into the bowel and makes the stool softer and easier to pass, thereby providing relief from constipation. Thus, it relieves constipation. Lubilax 24mcg Capsule also helps in normalizing bowel movements.

✔️ Side effects of Lubilax 24mcg Capsule

• Nausea
• Dizziness
• Headache
• Abdominal pain and swelling
• Flatulence
• Increased heart rate
• Edema
• Abdominal distension
• Diarrhea
• Flatulence
• Tiredness, dry mouth
• Chest discomfort/pain
• Shortness of breath
• Abdominal discomfort
• Hot flushes
• Upset stomach
• Excessive sweating

✔️ Quick Suggestions:

• Lubiprostone should preferably be taken with meals to reduce symptoms of nausea
• Aim to have a well-rounded diet that incorporates a variety of fresh fruits and vegetables.
• Stay properly hydrated by drinking enough water and other fluids throughout the day.
• Engage in regular physical activity to maintain your fitness level.
• Make sure to get enough sleep to support your overall health and well-being.
• Seek medical attention if you experience severe diarrhea, breathlessness (dyspnea) or difficulty in breathing, chest pain, or tightness in the chest during treatment.
• You should be thoroughly examined to confirm the absence of obstruction (e.g. gall stones, hernia, Crohn's disease, diverticulitis, polyps, impacted bowel movement, etc.) before starting lubiprostone treatment.
• Lubiprostone is not recommended in children under 18 years of age.
• Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.

✔️ Indication of Lubilax 24mcg Capsule

• Chronic idiopathic constipation
• Opioid-induced constipation in patients with chronic non-cancer pain
• Irritable bowel syndrome with constipation in women

✔️ Pharmacology

Lubiprostone is a chloride-channel activator that works locally to increase intestinal secretion. It does this by increasing intestinal motility, which aids stool passage and relieves the symptoms of chronic idiopathic constipation.

✔️ Dosage & Administration of Lubilax 24mcg Capsule

Adult Dose: 

• For chronic idiopathic constipation, the recommended dose for adults is 24 micrograms (mcg) twice daily.
• For irritable bowel syndrome with constipation, the recommended dose is 8 mcg twice daily.
• For the treatment of opioid-induced constipation in patients with chronic noncancer pain, the recommended dose is 24 mcg twice daily.
• For patients with mild hepatic impairment, no dosage adjustment is needed.
• For patients with moderate hepatic impairment (Child-Pugh B), the recommended dose for chronic idiopathic or opioid-induced constipation is 16 mcg every 12 hours. At the same time, no dosage adjustment is required for IBS-C.
• For patients with severe hepatic impairment (Child-Pugh C), the recommended dose for chronic idiopathic or opioid-induced constipation is 8 mcg every 12 hours. In comparison, the recommended dose for IBS-C is 8 mcg every 24 hours.

Child Dose

• Lubilax 24mcg Capsule is not recommended for use in children and adolescents (aged 18 years and below) as the safety and effectiveness of Lubilax 24mcg Capsule have not been studied in this group

Take Lubilax 24mcg Capsule as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. The correct dose and duration for you will be decided by your physician for you depending on your age, body weight, and disease condition.

✔️ Interaction

Lubilax 24mcg Capsule has the potential to interact with some medications and medical conditions. It is important to inform your doctor about all your medications, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medications that may interact with Lubilax 24mcg Capsule include the anticancer drug idelalisib and painkiller methadone.

Additionally, Lubilax 24mcg Capsule should be used with caution in individuals with intestinal obstruction, appendicitis, intestinal blockage, bowel inflammation, liver impairment, and dyspnea (shortness of breath). If you have any of these medical conditions, your doctor may need to adjust your dosage or closely monitor you for potential side effects. It is essential to always follow your doctor's instructions when taking Lubilax 24mcg Capsules to avoid any possible interactions or complications.

✔️ Contraindications

Lubiprostone is not recommended for people who have a mechanical gastrointestinal obstruction, whether they know it or not.

✔️ Pregnancy & Lactation

Category C pregnancy. Whether lubiprostone is excreted in human milk is unknown. Human milk-fed infants should be monitored for diarrhea because lubiprostone increases fluid secretion in the intestine and intestinal motility. When Lubiprostone is given to a nursing woman, it should be done with caution.

✔️ Precautions & Warnings

• Firstly, do not take Lubilax 24mcg Capsule if you have a known allergy to any of its ingredients.
• If you are pregnant or breastfeeding, consult your doctor before taking this medicine, as the benefits and risks need to be carefully weighed.
• Lubilax 24mcg Capsule should not be given to children as its safety and effectiveness have not been established in this population.
• While taking Lubilax 24mcg Capsule, it is important to drink plenty of fluids (at least 6-8 glasses) to avoid dehydration.
• However, do not take Lubilax 24mcg Capsule if you have severe dehydration, appendicitis, blockage in the intestine, blocked bowel or inflammation of the bowel, and liver disease.
• Only take Lubilax 24mcg Capsule as prescribed by your doctor, and inform them if you experience any light-headedness or chest tightness, or if you feel short of breath.
• It is also important to keep your doctor informed about your health condition and any other medicines you may be taking to avoid potential side effects or interactions.

✔️ Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.